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For this slice, maximal uptake (maximal counts within the tumour: TUmax) was determined and the ratio to the background (BG) was calculated.
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It is important to define this level, since suboptimal therapeutic amounts will not lead to maximal uptake and maximal absorbed doses in the tumours.
Therefore, inflammation prevents maximal uptake of oxygen by cells.
Finally, we assume that the maximal uptake rate of A is 1 (β1 = 1).
Cells were then incubated with 1 μM diSC3-5 for 1 hour, for maximal uptake of dye.
FM, fibromyalgia; Km, Michaelis constant; Vmax, maximal uptake rate of specific serotonin transporter.
The uptake by the synaptosomes at 30 min in [H]dopamine only was taken as maximal uptake (100%).
The salivary excretion factor (SEF) was determined as the maximal excretion activity per gland as a function of the maximal uptake [ 13].
These concentrations are lower than those at which the half maximal uptakes occur.
In contrast, normal tissue uptake was maximal at day 1.
In all cases the potentiation of uptake was maximal for 4',5'-ODCQA.
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