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The onset time to maximal twitch depression and the time to clinical recovery were compared between the 2 groups.
After 10 days of sepsis, the fast-twitch extensor digitorum longus muscle has a smaller cross-sectional area, increased fatigability, and reduction in maximal twitch contraction among other abnormalities.
The muscle was adjusted to the optimal length (L0) at which maximal twitch force was achieved.
Optimal length, i.e the length producing maximal twitch tension, was determined.
Muscle length was adjusted to obtain the maximal twitch response, and this length was measured and recorded as optimal length.
The optimal stimulation intensity (45.0±9.7 mA; range: 30 mA to 65 mA on KE and 46.5±6.5 mA, 35 mA to 60 mA on PF) was determined from maximal twitch torque measurement (see below) and was reassessed before each session including POST.
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The current will then be increased by 25% to ensure supra-maximal stimulation of the intramuscular nerve branches, and this value will be used in all subsequent supra-maximal twitch trials.
Maximal isometric twitch force (Pt) was estimated according to the tendogram of the TS isometric twitch response to a single electrical stimulus applied to the tibial nerve (Fig. 1a, left panel).
Maximal isometric twitch force (P t) was estimated according to the tendogram of the TS isometric twitch response to a single electrical stimulus applied to the tibial nerve (Fig. 1 a, left panel).
The sarcomere length was set to 2.1 μm to ensure maximal active twitch force (Dou et al., 2008).
Significant increases in maximal isometric twitch TPT and decreased 1/2 RT were maintained during a 120-day HDT.
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