Sentence examples for maximal transactivation by from inspiring English sources

Mutation of residue K30 of CRTR-1 was sufficient to abolish detectable sumoylated CRTR-1 in COS-1 cells and resulted in increased activity in both ES and COS-1 cells, suggesting that sumoylation at K30 blocks maximal transactivation by CRTR-1.

Thus, the Ets1 binding site at −122 bp of the murine MMP13 promoter is essential for maximal transactivation capacity of Ets1.

Prenzel, N. et al. EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF.

Ohtsu, H., Dempsey, P. J. & Eguchi, S. ADAMs as mediators of EGF receptor transactivation by G protein-coupled receptors.

The HMG domain of Sox2 binds the DNA to facilitate transactivation by the cooperative transcription factors such as Oct3/4.

These observations suggest that MST1 plays a role in FoxO3 transactivation and that BRAFV600E inhibits FoxO3 transactivation by suppressing MST1 activity.

We show that Tbx1 modulates negatively Smad1-dependent transactivation by interfering with Smad1-Smad4 interaction.

Two of these genes, KBTBD10 and PLN, showed clear transactivation by NUP98-HOXA9 (Fig. 1).

When this reporter system was used, Teashirt3 also inhibited the transactivation by Gal4-FE65 (Fig. 3C).

Transactivation by Smad2 is independent of the Smad binding element.

Cumate addition abrogates DNA binding and therefore transactivation by cTA.