Sentence examples for maximal tolerated doses from inspiring English sources

injection using optimal and maximal tolerated doses of each drug.

In addition, patients will be placed on the maximal tolerated doses of lisinopril, losartan or atorvastatin, based on measurements of blood pressure, serum potassium, creatinine, and cholesterol concentrations.

Years 1996 2005 was a period of most intensive studies, aimed at establishing maximal tolerated doses of IL-12, optimal treatment schedule, and the most susceptible tumors.

Her IOP remained over 50 mmHg in the right eye even under treatment with oral acetazolamide and maximal tolerated doses of topical anti-glaucoma medications.

Maximal tolerated doses in escalating dose protocols ranged, in relation to the treatment schedule, usually between 250 and 500 ng/kg.

However, the AIx benefits compared with metoprolol may not extend to individuals with hypertension and diabetes mellitus who are receiving maximal tolerated doses of renin-angiotensin-aldosterone system (RAAS) blockers [ 22].

In a phase 1 trial the maximal tolerated dose is determined based on clinician assessment of toxicity during the first cycle of treatment.

To identify the maximal tolerated dose level of preoperative intensity-modulated radiotherapy combined with capecitabine and oxaliplatin and to evaluate the efficacy.

At that point in time he was under chronic treatment with verapamil (maximal tolerated dose of 560 mg/day) for 6 months with only a mild effect on attack frequency.

The maximal tolerated dose was not reached.

The maximal tolerated dose was 1.2 mg m-2 day-1.