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161Tb decays, with a half-life of 6.9 days, by the emission of low-energy β−-particles (Eβ− av = 154 keV [3]) with a maximal tissue range of 0.29 mm and a LET of around 0.32 keV/μm, which is suitable for the treatment of metastasized malignancies.
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This allows maximal tissue penetration, and, therefore, desired therapeutic results.
True determination of the maximal tissue concentration is questionable on this basis.
Computer software automatically calculated the following parameters: SIrel= SImax SI0)/SI0 × 100 (maximal tissue enhancement from baseline).
The enhancement of cytotoxicity under hyperthermia and a maximal tissue penetration of 2 mm.
In vivo studies on radioimmunotherapy with the β-emitting radionuclide 177Lu (maximal range in soft tissue, 1.8 mm) with the aim of treating colon carcinoma metastases resulted in prolonged survival [16, 17].
Conjunct motion in the two associated planes was recorded continuously throughout maximal primary range movements.
The primary outcome measure was a change in maximal active range of motion (AROM).
Data in parentheses represent maximal dose, range (μg/minute for norepinephrine and μg/kg.min for dobutamine).
The two investigators received information on symptom location and maximal joint range of motion.
SEM from the maximal and range CoP velocity range between 285.57 mm/sec and 414.73 mm/sec.
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