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The mean maximal time difference for testing was 106 (0 405) min on any of two study days and within 90 min in 38 (66%) subjects.
To control for diurnal variation in lung function, all tests were to be conducted at approximately the same time of day, defined as a maximal time difference of 90 min or less on any of two study days.
For EVH and field exercise tests, the interval between tests was 9.2 (2–20) days, the mean maximal time difference was 149 (0 340) min and was within 90 min in 13 (39%) subjects.
Similar(57)
The maximal time-matched mean differences from placebo in QTcF change from baseline for indacaterol 150 μg (2.66 ms) and 300 μg (2.98 ms) doses were observed at 2 h post-dose (Table 2).
The duration of the extracellular action potential (APex) corresponding to the intracellular half-width (see figures 1, 2 and 4) was calculated as the time difference between the minimal and maximal changes in the extracellular waveform.
Time difference: +1hr.
Time difference: - 4 hours.
Time difference: GMT -3hrs.
Time difference: +7 hrs.
The time difference helped.
Assume that T ∗ > 0 is the maximal time of existence.
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