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Using this formula, the maximally-achievable score is 4.55 (maximal suppression of 128Q cytotoxicity, i.e. 100% responsiveness) and the minimally-achievable score is -1 (maximal aggravation of 128Q cytotoxicity).
Chan, R. et al. Co-expression of anti-NFκB RNA aptamers and siRNAs leads to maximal suppression of NFκB activity in mammalian cells.
Maximal suppression of FHB and grain contamination by deoxynivalenol (DON) mycotoxin results when fully emerged heads of winter malting barley are sprayed with full label rates of Caramba or Prosaro fungicides.
The highest UP pigment concentration increased lipid peroxidation and the incidence of micronuclei by more than 70% with maximal suppression of cell proliferation.
Androgen deprivation therapy (ADT), which involves the maximal suppression of circulating testosterone, underpins the treatment approach to metastatic hormone sensitive prostate cancer.
It was necessary that Con A suppressor cells be present early in the process of activation of human B cells toward antibody syntheses, but maximal suppression of the PFC response occurred later in the culture period.
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The maximal suppression on intrinsic hepatic clearance of CYP2C9 was 17%, occurred at ∼70 hours, and lasted for ∼9 days.
The maximal suppression on intrinsic hepatic clearance of CYP3A4 was 28%, occurred at ∼48 hours, and lasted for ∼1 week.
Similarly, the maximal suppression on intrinsic hepatic clearance of CYP1A2 was 9%, occurred at ∼48 hours, and lasted for ∼1 week.
Simulations were also performed with the highest IL-6 profile; the projected maximal suppression on hepatic intrinsic clearance of CYP3A4, CYP1A2, and CYP2C9 was 20%, 19%, and 14%, respectively.
In order to determine insulin sensitivity, using regression analysis, the insulin concentrations causing half-maximal suppression of serum NEFA (INS-½-max NEFA) were calculated for each subject.
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