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However, studies employing the CBI indicate a relatively strong stimulus (up to 80% of maximal stimulator output) is required to effectively stimulate the cerebellum [6].
The induced EF clearly depends on stimulation intensity, expressed as percentage of the maximal stimulator output, on the relative position between subject's head and TMS coil, and on the geometrical and physical properties of head tissues between the stimulator and the cortical surface.
In all subjects, stimulation intensity was set at 70%% of the maximal stimulator output, corresponding to the mean intensity used in Exp1M1right and Exp2M1left.
Stimulus intensities then were reduced in steps of 2% of maximal stimulator output.
MT ranged from 30 to 48% of maximal stimulator output in treated and from 32to55%5% in the non-treated group.
For this purpose TMS was initially applied with a stimulus intensity of 20% of maximal stimulator output and further increased in steps of 5% until phosphenes were reported.
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TMS pulses were delivered at 60% of maximum stimulator output (maximum stimulator output equals ∼2 Tesla).
In some patients, the threshold was either very high or could not be determined; here, magnetic stimulation at the maximum stimulator output was used.
The mean motor threshold (RMT) was 53.3% (SD 7.15) of the maximum stimulator output intensity; hence mean stimulation intensity for the experiment was 63.9% (SD 8.62).
This procedure resulted in stimulation intensities of 48 61% of maximum stimulator output.
The average stimulation intensity was 63.25% of maximum stimulator output (range 58%66%%).
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