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At steady state, either during starvation or during sustained maximal stimulation, the influx is in equilibrium with the efflux.
Under maximal stimulation, the VTG protein also undergoes a level of induction up to a 1,000-fold 1,000-foldn thigherthanhe VthatRNA transcript (Thomas-Jones et al. 2003).
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As shown in Fig. 4 B, the DDX3ΔINS mutant protein showed a significant reduction (3.2- fold) in the maximal stimulation of the ATPase activity by ssDNA, with respect to DDX3wt.
Muscle bundles were divided into two groups, one for the establishment of the force-length relation during sub-maximal and maximal stimulation, and the other for measurement of staircase and posttetanic potentiation.
Study visit 2 is designed to measure the baseline circulating RAS under conditions designed to induce maximal stimulation of the circulating RAS: restricted dietary sodium intake and upright posture.
Yet, maximal stimulation of the reconstituted transporter was achieved at lower drug concentrations, suggesting that its substrate affinity and/or coupling mechanism between transmembrane and nucleotide-binding domains were favored upon reconstitution.
In 5-day MMC, 130% stimulation of PG synthesis occurred at 2.5 μg/ml PPS (P < 0.0001), while 5.0 μg/ml PPS achieved maximal stimulation in the 7-day and 10-day cultures (P < 0.05).
Gmax and C50GLY denote respectively the maximal stimulation effect and the Ep concentration that produces 50% of the maximal response.
More broadly, however, the focus on minimal versus maximal stimulation is perhaps besides the point; the real goal of treatment should be "optimal" stimulation, an approach that requires tailoring the treatment plan to each individual couple.
Maximal stimulation strength increased the mean amplitude and mean decay time constant of oIPSCs (red circles; p<0.04 for both, Wilcoxon signed-rank test), suggesting that the ability of GATs to limit pooling and/or spillover of GABA at dopaminergic synapses is compromised at high light stimulation intensities.
For the maximal stimulation of GLP-1 secretion from GLUTag cells, the KCl concentration in the secretion media was raised to 30 mM while reducing the NaCl to keep constant osmotic concentrations.
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