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During evolution, spatial correlation with hemodynamic signal only exists briefly at the maximal spread of the VSD signal.
In general, we find that during all points in the evolution of the seizure, the area of CBV signal was slightly larger than the maximal spread of each membrane potential wave (Fig. 8).
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We observed that targeting KCa3.1 induced significant reductions of the tumor-infiltrated area and reduced the maximal spreading of GBM in the cerebral parenchyma.
However, after 2 h, controls had reached a near maximal spread cell area of 1645.5 μm ± 231.3 while the talin1 knockdown cells were markedly smaller (465.0 μm ± 93.3, p = 0.0001), a difference that was maintained for the entire 14 h period (Fig. 2B).
Only difficult and time-consuming measurements, as performed for example in the G dataset, lead to an accurate assessment of the maximal lateral spread of a root system (Phillips et al. 2014).
The tumours were serially sectioned in the transverse plane and the section with maximal lateral spread of tumour was identified.
Those aged 13 to 14 years showed a wider spread of maximal ICCs, with some resembling one of the teenage or adult groups, and the remainder resembling younger cases.
Pathological staging was undertaken by a consultant pathologist according to the TNM classification and the pathological extent of maximal extramural spread in mm and the distance of tumour to the nearest CRM was measured.
Typically four to six Wingate tests are performed separated by 4 minutes of rest, for a total of 2 to 3 minutes of maximal exercise spread over 15 to 30 minutes.
Classic SIT protocols can require as little as 2 to 3 minutes of maximal exercise spread over 15 to 30 minutes.
Radial profiles were calculated for maximal intensity projections of fluorescence in order to calculate the spread of the various PLP deletion constructs around the centriole.
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