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Different types of converter materials were examined with the aim to reach maximal spatial resolution at reasonable detection efficiency.
The maximal spatial resolution along the z-axis is determined by the detector collimation used at image acquisition and for technical reasons is slightly thicker than this.
We found that in different cellular compartments the typical density of detections within 2000 frames of 25 ms ranged from ρ = 2×10−3 to 8×10−3 nm−2, which results in a theoretical maximal spatial resolution of 44 to 90 nm (or 62 to 126 nm for 1000 frames) considering a constant density probability [28].
Therefore, peripheral innervation density cannot readily explain the maximal spatial resolution for pain on the fingertips.
Potential limits of F-FDG-PET/CT are lesion dimensions, because of PET maximal spatial resolution of 4 mm.
Another factor adding to the limited peripheral acuity is that the responses of rods are usually pooled to increase sensitivity to light at the expense of spatial resolution; while the 1 1 correspondence in the fovea allows for maximal spatial resolution, the ratio of photoreceptors to ganglion cells can be as low as 130 1 in the periphery [ 27].
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In the imaging system, the maximal spatial frequency is determined by the resolution of the microscope, and for the particular imaging condition we used the resolution is ∼0.2 µm in the x-y plane, and ∼0.75 µm along the z axis [18].
Spatial resolution was measured by imaging a Ronchi grating and calculating the distance across the edge over which intensity ranged from 10% to 90% of the maximal value.
Indeed, when the spatial resolution is insufficient relatively to the maximal curvature radius of fiber bundles, tracts that cross in reality may kiss in the tractography reconstruction and vice versa, thus creating aberrant solutions.
We hypothesized that utilization of the maximal optical magnifying ratio during magnifying endoscopy provides the best spatial resolution, and increases the diagnostic ability to differentiate between cancerous and non-cancerous mucosa.
As recently shown, the use of newer improved EPI technology, dedicated surface coils and optimized sequences enables a maximal reduction of EPI-related artefacts at a relatively high spatial resolution [ 8, 23– 27].
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