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Receiver operating characteristic (ROC) curve analysis was used to evaluate the cutoff value of HCG with maximal sensitivity and specificity to differentiate between viable and non-viable pregnancies.
The damage done by noxious influences may result in actual breakdown of cells in a region of maximal sensitivity and may also lead to a depression of the developmental potential of the cells.
In contrast, a two-step format requires very low coating concentrations and higher conjugate concentrations to achieve maximal sensitivity and suffers from significantly reduced sensitivity at higher coating concentrations.
These variables, when incorporated into a bio-clinical score, had a maximal sensitivity and specificity of 54 and 89%.
Additionally, using a cut-off for instability at ≥2/5 markers to define MSI results in maximal sensitivity and specificity for this assay, particularly for samples mutant for MSH6.
Logistic regression analysis indicated maximal sensitivity and specificity for prediction of ACL injury risk.
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Previous work has quantified the contribution of each site to the overall wavelength of maximal sensitivity (λmax) and it is therefore possible to identify opsins within subfamilies with different spectral sensitivities by comparing their amino acid sequences.
Similarly, the curve for survival after 5 years (Fig. 1(C)) showed that the score 6 of CIAPIN1 expression level provided a maximal sensitivity (0.61) and specificity (0.73).
The ROC curve for non-local recurrence within 5 years (Fig. 1(C)) showed that the score 7 of CIAPIN1 expression level provided maximal sensitivity (0.63) and specificity (0.74).
At this value maximal sensitivity 54% and specificity 73% were attained.
These results indicate that reduced TrxR is required for maximal sensitivity to NAPQI and that the selenocysteine-containing C-terminal redox center of TrxR is critical for enzyme inhibition.
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