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The assumption was that selection for divergence for maximal running capacity would capture many contrasting features between the strains for numerous complex physiological and behavioral elements.
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The study compared 12 high capacity runners (HCRs) and 12 low capacity runners (LCRs) from generation 18 of selection that differed by 615% for maximal treadmill endurance running capacity.
Briefly, endurance running capacity was assessed on a treadmill and the total distance run during the test was used as a measure for maximal aerobic exercise capacity.
Reduced maximal running velocity and endurance capacity in Atgl−/− mice is not due to defective muscle contraction [24].
The second visit was used to assess their maximal running speed and maximal aerobic power.
The maximal running speed and distance were calculated.
The parameters recorded daily from the wheel running behaviour included the total number of runs, total distance run, maximum run interval and the maximal running velocity (Vmax).
Maximal running distance was significantly reduced in old PPARβ−/− vs PPARβ+/+ mice, whereas the maximal speed was unchanged.
The speed at which each mouse stopped running was considered to be the maximal running speed (Vmax).
Maximal running velocity increased 13.5% throughout the training and was similar in both training groups.
Functional performance was defined as the maximal running velocity attained at a 40% inclination.
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CEO of Professional Science Editing for Scientists @ prosciediting.com