Sentence examples for maximal responses observed from inspiring English sources

In murine eosinophils of IL-5 transgenic mice, eotaxin increases the CD11b and VLA-4 expressions, with maximal responses observed 1 h (CD11b) and 2 h (VLA-4) after incubation with eotaxin, suggesting that Mac-1/ICAM-1 interareions are dominant at early time, whereas VLA-4/VCAM-1 becomes predominant at later time-points during eotaxin-induced eosinophil recruitment [ 37].

First, the basal activities observed for both receptor classes were close to the maximal response observed for the α-factor-activated native Ste2 receptor, hence the response may be already saturated.

As demonstrated in Figure 1, LA caused [Ca2+]i rise in HM cells and the amplitude of the LA responses was dose dependent (Figure 1A and B) with maximal response observed at 30 60 µM.

Similar to the kinetics of inflammation, the pain response following reactivation continued to increase significantly and remained elevated throughout the 10 day period, with a maximal response observed on day 45 (96 hr post re-challenge) (P < 0.01).

I3C rapidly prevented the proliferation of 10AT-Her2 cells with a maximal response observed by 72 hours, whereas, proliferation of the control 10AT-Neo cells remained relatively unaffected by I3C treatment.

In each nerve, a brief pulse (30 s) of ATP (100 μM) was used at the beginning and end of the experiment to confirm the viability of the nerve, and in this way the responses to mGluR agonists could be compared to the maximal response observed in ATP, in paired recordings from individual cells [19].

For VU0422288, we were able to fit data by applying a modified version of the allosteric ternary complex model (eq 3) to the shifts in agonist potency in the presence of modulator, which allowed us to assess affinity and cooperativity as a combined αβ parameter while setting the Em value to a level just above the maximal response observed.

Due to these apparent changes in KA values, we reanalyzed the calcium assay data shown in Supporting Information Figures S3 S5 using eq 2 by allowing the α value to be shared across data sets and setting the maximal response (Em) to the maximum response observed with any agonist/modulator combination.

Maximal responses were observed 14 days after the boost.

As an example for a typical steroidal estrogen, estriol exhibited the full range of effects, producing the maximal proliferative response observed with E2, which was routinely used as a positive control.

The highest concentration, dose 3 or ED10, was the dose where 10%% of the maximal response was observed, dose 2 or ED5, where 5%% of the maximal response was observed, dose 1 or ED0, represented half the maximal dose where no effect was observed, and dose 0, where no drug was present (Table  1).