The combined response of both cone cells and rod cells gives maximal response and is produced by the white standard flash (10 seconds between the flashes) [ 4].
In mesenteric rings, the maximal responses to ACh was reduced in SDD animals while the run training for 12 weeks reversed the impairment of the relaxation responses produced by high caloric diet in TRD group.
In sedated patients, after the warm-up, the intensity that produced a maximal response was determined, and the 60% of that value was used as the starting point.
The minimum concentration of E2 that produced a maximal response of the protein ions in MCF-7 cells was 20 pM, and this is similar to that determined using the E-Screen assay on these cells.
The standard dose produces a maximal response in control mice; thus, the reduced dose was used to test the hypothesis that the inflammatory response would be greater in Hsd11b1−/− mice.
Lamprey insulin produced the same maximal response as serum or human insulin, while the maximal stimulation by hagfish insulin reached only 75% of that of human insulin (the difference was not statistically significant).
Final body weight, heart rate and blood pressure, relative weight of the left ventricle and adrenal glands, normalized diameter, basal tension, and contraction data as well as the maximal response (Emax) and the concentration that produced a half maximal response (pD2) were analyzed using two-way ANOVA and Bonferroni post-hoc test.
The K+ concentration producing a half maximal response was also similar in resistance vessels from STZ-treated (30 ± 4 mM) and control (36 ± 5 mM) arteries.
Xamoterol, ZD 7114, and bucindolol were the most efficacious partial agonists producing maximal responses that were 59, 49, and 49% respectively, of that produced by isoprenaline.
For each concentration-response curve, the maximal effect (Rmax) and the concentration of agonist that produced 50% of the maximal response (log EC50) were calculated using non-linear regression analysis (GraphPad Prism, GraphPad Software, Inc., San Diego, CA).
