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Also, luring should induce closer approach by prey; and aspects of the behaviour (e.g. frequency of movement of the lure) should have been fine tuned by selection to induce maximal response from prey.
For each individual patch, currents were normalized to maximal response from that patch.
For each individual patch currents were normalized to the maximal response from that patch and plotted versus inverse radius.
To correct for the different immobilization densities of each surface, 200 nM mAb D7324 was first passed over each surface and the sCD4 response was normalized to the maximal response from D7324.
Concentration-inhibition data were fit to the equation: I = I max/(1+ (X/IC 50) n) where I represents the current response at a given concentration of inhibitor, X; I max is the maximal response in the absence of inhibitor; IC 50 is the concentration of inhibitor present that still allows a half maximal response from odorant; n is the apparent Hill coefficient.
Pooling all experiments with the highest concentration of Xestospongin C (20 μM, n = 6) revealed a statistically significant (P < 0.025, one-tailed test), but very small, inhibition of the maximal response from IP3R1, and an even smaller increase in pEC50 for IP3R1 and IP3R3 (Table 3 and Supporting Information Table S1).
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These concentrations were previously found to elicit maximal responses from these cells [ 6, 12].
Currents from individual patches are normalized to the maximal response for each patch.
Data from HEK293OFF cells studies are presented as the percentage of the maximal response for each agonist.
(j) Fraction of the maximal response recorded from individual layer 2/3 pyramidal neurons following stimulation of ChR2-expressing SST + cells in SstCre Mafbfl/+ RCE and SstCre Mafbfl/fl RCE mice at increasing LED intensities.
In addition to a lower ETP50, dbh−/ − larvae also exhibited an increased maximal response fraction, from 0.43 for dbh−/ − compared to 0.34 for dbh+/+ (p < 0.0001 by extra sum-of-squares F test).
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