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This media (NPC Growth media) was used to enhance growth conditions for maximal proliferation of cells.
The results suggest that HMGA2 expression is necessary for maximal proliferation of WZA LacZ cells.
Maximal proliferation of LNCaP-abl cells was achieved at 0.001 n M of the synthetic androgen methyltrienolone (R1881), whereas 0.01 n M of this compound induced the same effect in parental cells.
Thus, it is possible that the basal level of IL-6 present in the host is sufficient for optimal T-cell proliferation or that IL-6 production by DCs is not necessary for maximal proliferation of CD8+ T cells.
The observation that the presence of PTP-1 did not further increase CD3-CD28-dependent T cell response of young subjects can be explained by the absence of an effect on pLck-Y394 levels thus, on the already maximal proliferation of these cells.
Similar(55)
Half-maximal proliferation of TF-1 cells was observed at 1 ng/mL muNGF and dilutions of NV-01 (2.5 ng/ml to 0.002 ng/ml) were titrated against this concentration of NGF.
Again, mock-infected MDDC induced minimal levels of CD4+ T cell proliferation (median of 0.4% of proliferated cells), and SEB-treated MDDC induced maximal proliferation (median of 93.1%).
Before the transition to metazoans, natural selection shaped one-celled organisms for whatever traits maximized their representation in future generations, especially maximal proliferation, invasion of adjacent spaces, and transmission to open niches.
Cryopreservation did not alter the maximal proliferation capacity of ConA or αCD3/αCD28 stimulated PBMC, whereas it did delay the proliferation.
Their study saw reduction of de novo DNA synthesis without alterations to cell numbers and viability and restoration of maximal proliferation upon serum supplementation.
We used a 100-pM concentration of E2, which generates near maximal proliferation, in combination with increasing concentrations of DHT and observed an inverse dose-response relationship between androgen concentrations (log-transformed) and cell proliferation (regression coefficient = -0.887; P < 0.001).
Related(20)
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