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Similar results were obtained for ratios obtained by maximal plasma levels measured during RT divided by the corresponding pre-RT values (data not shown).
59 Ghrelin reaches it maximal plasma levels before meals in order to stimulate food intake.
The time needed to reach maximal plasma levels was significantly prolonged after food intake (median 3.1 h, range 2.8 6.1) compared to fasted conditions (2.0 h, range 1.1 8.1) (P = 0.013).
Following oral administration of imepitoin at a dose of 30 mg/kg in healthy Beagle dogs, high plasma levels were observed within 30 min, but maximal plasma levels were only reached after 2−3h following a prolonged absorption time [ 101].
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Oral uracil tegafur generates a higher maximal plasma level of fluorouracil than protracted intravenous infusion of fluorouracil at a dose that is equimolar to the amount of tegafur in uracil tegafur (Ho et al, 1998).
Maximal CRP plasma levels observed during ICU stay did not differ between septic shock patients with new-onset AF and those who maintained SR (Table 2).
After subcutaneous injection, maximal curcuminoid plasma levels of 23 μM and brain levels of 8 nmol/g were observed at 30 minutes after injection and curcuminoids remained detectable for 2 to 3 h.
dosing in rabbits of ramoplanin alone and ramoplanin with penicillin resulted in maximal ramoplanin plasma levels (Cmax) of 28 μg/ml (11 μM; 14× MIC) and a 12-h concentration (C12) of 6.4 μg/ml (2.5 μM; 3× MIC) (19) when using the agar dilution method.
The day 8 PET scan started at 3 h post-dosing of oral lapatinib to coincide with the known maximal plasma lapatinib level (C max).
Maximal average prednisolone plasma levels (at 9 am after the 10-mg dose) were 30 to 35 ng/mL.
The therapeutic effect was observed within 1 week and was dependent on the plasma levels, being maximal at concentrations of 300 400 nmol/l.
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