Sentence examples for maximal plasma concentration from inspiring English sources

Vigabatrin had an oral absorption fraction (Fabs) of 75 80%, and the maximal plasma concentration (Cmax) was reached within 0.5 1.0 h (tmax).

When dosed orally in mice at 50 mg/kg twice a day (BID), 48 showed an unbound maximal plasma concentration (Cmax) >15-fold over its cell EC50, thereby providing a robust chemical probe for studying KDM5 biological functions in vivo.

A significant increase in both maximal plasma concentration of drug and area under the drug concentration time curve (AUC) was shown when the particle size was reduced from micrometer to nanometer.

LND is rapidly absorbed with the maximal plasma concentration occurring at a median time of 0.6 to 1.5 hours after oral administration in healthy human subjects.

By Week 4, mean peak plasma concentration (Cmax) was 865 µg/mL and time of maximal plasma concentration (Tmax) was 39.4 hours.

The maximal plasma concentration was 199 ng rt-PA/ml.

AUC: Area under the curve; Cmax: Maximal plasma concentration; HPLC: High performance liquid chromatography; t0.5: Elimination half life; Tmax: Time of maximal plasma concentration.

Time to maximal plasma concentration in the present study was reached after 1.25 hours, with a maximal plasma concentration of 46.3 ± 14.0 ng/ml.

Coadministration of tolvaptan has been shown to increase the maximal plasma concentration of ketoconazole by 248%.

In cats maximal plasma concentration has been detected at 10 45 min [ 32].

Administration occurred 1 h before testing to reach maximal plasma concentrations.