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The emission maximum for W7F, corresponding to the pH at which the population of the molten globule intermediate is maximal, occurs at higher pH (4.4) than for wild-type apomyoglobin (pH 4.0), reflecting destabilization of both the native state and the intermediate by the W7F mutation.
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The maximal velocity occurs at the top point of seepage face.
We find that maximal adhesion occurs at intermediate densities of both sialyl Lewis X and anti-ICAM-1, owing to synergistic binding effects between the two ligands.
Antibody-dependent enhancement in FIPV demonstrates a bell-shaped curve with increasing dilutions; maximal enhancement occurs at subneutralizing titers (34).
However, assuming that the maximal response occurs at doses higher than 100 nM spiradoline, we can estimate that the EC50 would be at least 13.44 nM.
In Figure 10, the maximal variance occurs at the origin (hf = hm = h = 0) of the cell with s 1 f = s 1 m = s 1 = 0.5.
The obtained bell-shaped curve indicates that maximal activation occurs at a 1 1 molar ratio, but excess ClpT1 somehow inhibits the increase in ATPase activity.
Although maximal binding occurs at an apparently uniform phase, the peak transcriptional phases of CLK BMAL1 target genes are heterogeneous, which indicates a disconnect between CLK BMAL1 DNA binding and its transcriptional output.
Previous studies had shown that the proliferation of hormone-sensitive prostate tumor cells (e.g., LNCaP cells) is biphasic and dependent on the dose of androgen, and maximal proliferation occurs at physiological concentrations (i.e., 1 nM R1881) [ 59- 61].
When their response to oestradiol at the time of regrowth is retested, it is found that the dose response curve is shifted to the left and maximal proliferation occurs at approximately 10-14 mol/l, instead of the approximately 10-9 mol/l in wild-type MCF-7 cells.
Half-maximal binding occurs at 2.4 microM free Ca2+ whereas up to 1.2 mM Mg2+ has no effect on binding.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com