Sentence examples for maximal occupancy from inspiring English sources

The relationship between GlyT1 occupancy (in percent) and dose of SSR504734 was expressed by the equation: Occupancy  % = O max × C p C p + K d, where Omax is the assumed maximal occupancy (i.e., 100%), and Cp is the dose at which occupancy becomes 50%.

In the absence of Bdf1, however (grey bars), maximal occupancy at the large promoter (+790) increased to a level comparable to the full-length promoter (−11).

To maintain maximal occupancy of glucocorticoid receptors in tissues, a 1 : 1 mixture of betamethasone phosphate and betamethasone acetate is optimal.

In the DMSO samples, all r-proteins within a given subunit displayed highly correlated occupancy patterns with maximal occupancy corresponding to 'peak' fractions as determined by rRNA absorbance.

Such a reverse protonation scenario would result in an identical pH rate profile because both of these two protonation states of the substrate and enzyme would have maximal occupancy at pH 7.25, decreasing at both higher and lower pH values.

Similarly to animal studies, human PET and single photon emission computed tomography (SPECT) analyses revealed that LAI antipsychotics continuously and stably block D2Rs, albeit reaching consistently lower maximal occupancy rates than transient drug administrations (often ≤65%%) [ 123].

Partial agonists are defined as drugs that, at a given receptor, might differ in the amplitude of the functional response that they elicit after maximal receptor occupancy.

In the Rco1-degron strain (black bars), maximal Ada2 occupancy occurs at the full-length STE11 promoter region.

The data showed that binding kinetics and maximal TCR occupancy correlated well with Erk activation and this was in accordance with increased tetramer affinity (Supplementary Fig S2C and D).

As the stressor level increases further, causing stress-gene induction to reach its limit (such as due to maximal promoter occupancy by the transcription factor), the response profile of the controlled variable rises much more steeply.

The reason that the yields are so high for an assembly process that features bidentate ligand motifs on each component is that the rotaxane is the only possible product that allows maximal site occupancy[ 2a, 12] with a strict equimolar ratio of ligands and metal ion, and the reaction is carried out under thermodynamic control.