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Maximal interval change of TRACP 5b as a dichotomous variable (Δmax TRACP 5b × 38.59% versus ≤ 38.59%).
The maximal interval change within 6 months for serum TRACP 5b activity was used to stratify patients into two groups according to whether the interval change was greater or less than the LSC.
The maximal interval change between baseline and follow-up serum TRACP 5b activities (ΔmaxTRACP 5b) within 6 months of enrollment in each individual patient was calculated as [(baseline TRACP 5b activity - TRACP 5b activity at maximal alteration)]/baseline TRACP 5b activity × 100%.
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A different way of looking at the sensitivity to parameter changes is to look for the maximal interval around the "right" parameter value for which the cost function does not exceed a predefined threshold value.
The condition d(x e(x) > 0 generally holds in the whole maximal interval of continuity of the functions because the coefficients d(x) and e(x) do not change sign under very general conditions (see, for instance, [[8], Lemma 2.1]).
Step 2. By (3.23) there exists a maximal interval, where.
Denote by, where, the maximal interval of constancy of.
Hence there exists a maximal interval such that on.
We denote this curve by and the corresponding maximal interval of definition by.
We denote by the maximal interval of the solution of problem (3.1).
It follows from [26, Theorem 5.2.1] that (U_{2}(t)geq0) in its maximal interval of existence.
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