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Even at maximal induction levels there was no evidence of mistargeting.
Interestingly, the protective effect of NaHS root pre-treatment on heat stress tolerance in terms of transcriptional induction of defense-related genes was recorded 4 h after stress imposition, reaching maximal induction levels for most genes examined (except for CAT, NR, GS and DREB) after 8 h of heat stress.
Similar(58)
In addition, thiamine treatment induced pterostilbene synthesis with a maximal induction level observed also at 3 dpt.
When normalized to the initial control knockdown sample, INTS3 and INTS9 depletion increased the amount of JUNB mRNA at the zero time point over 2-fold, consistent with the steady state analysis, and the maximal JUNB induction level following 30 min of serum stimulation in INTS3- or INTS9-depleted cells reached ∼12- and 10-fold level of the serum-starved control knockdown, respectively.
Importantly, IRF1 knockdown prevented the maximal induction of TNF α mRNA levels upon BV6 treatment.
Both drugs enhanced the expression of Rad51 with the highest levels found at times of maximal induction of DNA damage.
Maximal induction of Flt-1 and Flk-1 transcript levels was observed on day 8 (2.7- and 4.2-fold respectively), whereas the level for Nrp-1, which can act as an enhancer for VEGF receptor signalling, had its peak expression already on day 4 of CIA.
We found that even at the lowest dose level (1 μg/kg) there was maximal induction of pSTAT3 in CD3+ T cells slightly higher than the in vitro positive control (Fig. 1a).
As shown in Figure 2A, increased GFPμ protein levels are first observed at 12 hours, and maximal induction is observed following 24 hours of exposure to 5 µM MG132.
Having shown that 5 ng of RNA encoding BMP4 was sufficient for maximal induction of PGCs or blood cells from animal caps, this level of BMP signalling was kept constant.
Upon addition of LPS, Slfn1, Slfn2, and Slfn4 mRNA levels were increased at all time points examined, with maximal induction after 24 hours LPS treatment.
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