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Importantly, only 0.1 μg/ml tetracycline was required for maximal induction demonstrating a higher affinity of tetracycline for YFP TetR than for wildtype TetR which required 1 μg/ml tetracycline for maximal induction.
The maximal induction upon exposure to 100nM 3-MC was 4.4-fold in comparison with carrier-treated cells.
Maximal induction of c-fos and c-jun mRNA by EGF occurred within 30 min of treatment with 10 ng/ml EGF.
Activation of both activator protein-1 (AP-1; c-Jun/c-Fos) and nuclear factor-κB (NF-κB) pathways is necessary for maximal induction of the TF gene.
Figure 10a shows the dependences of core loss on the frequency in the range 1 to 300 kHz measured at maximal induction 0.2 T.
PGE2 release was measured before and after maximal induction of COX-2 mRNA (3 hours after stimulation with IL-1β).
A treatment time of 40 min was used, since this results in a maximal induction of DSBs by both drugs.
Our results show that the calcineurin/NFAT pathway and PKC-delta pathway are required for maximal induction of RCAN1.4.
These motifs appear to function synergistically to provide maximal induction of Cyp26a1 in response to AtRA [33], [34].
Both drugs enhanced the expression of Rad51 with the highest levels found at times of maximal induction of DNA damage.
Classical activation of lung macrophages and maximal induction of IL-23 and IL-17 required both TLR4 and TLR9.
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