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However, higher concentration of n-butanol fraction showed maximal glucose uptake compared to both ethyl acetate and methanol fractions.
Maximal glucose uptake for each individual was calculated from mean glucose infusion rate over the final three 20-min intervals.
Taken together, these gene expression changes enable both maximal glucose uptake and a high efficiency of glucose utilisation.
During the final three 20-min intervals, the mean glucose infusion rate was used to calculate maximal glucose uptake for each individual.
Previous work has shown that this translocation is very sensitive to AMPK, and even very low levels of AMPK activation are sufficient to induce maximal glucose uptake [ 34, 52].
Direct comparison between rCBV mapping and other indicators of malignancy such as fluorodeoxylucose PET shows close agreement between local rCBV values and glucose uptake and significant correlation between maximal glucose uptake and rCBV[ 88 ].
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Of these, the first metabolic constraint is associated with the maximum glucose uptake rate (or glucose uptake capacity) (4) where F G is the maximum glucose uptake rate.
Moreover, recent imaging studies have shown that patients with impaired glucose tolerance need more insulin than healthy subjects for maximal brain glucose uptake [ 63].
MRGlucMAX is the hypothetical maximal value of glucose uptake rate, approached asymptotically as the glucose concentration increases to saturating levels.
In addition, the maximal rate of cellular glucose uptake (Vmax) can be modulated by activation or deactivation of GLUTs at the plasma membrane.
The curvature parameter K M is the Michaelis constant that represents the blood glucose concentration at which the glucose uptake rate is half the maximal (glucose-saturated) rate.
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