Sentence examples for maximal gene expression from inspiring English sources

Combinations of different transactivator and promoter variants from the same or different bacterial species resulted in a multitude of regulatory systems where l-tryptophan regulation properties, background noise, and maximal gene expression levels were significantly diverse.

Maximal gene expression 24 hours after electroporation was achieved at 300 V.

These 11 clusters represented maximal gene expression at different stages during the pregnancy cycle.

5-Azacytidine and TSA treatments were optimised for maximal gene expression and cell viability (data not shown).

Of the four clusters exhibiting maximal gene expression during involution, three were significantly associated with inflammation (IT), the acute phase response (IP and IL), or humoral immunity (IP).

To determine the true maximal gene expression level that can be reached with integration into pCA2.4 without toxicity effects, two reporter genes were considered (Fig.  1).

Of the three CpG sites, the second CpG site at −182 bp of insulin promoter is part of the cyclic adenosine monophosphate (cAMP) responsive element (CRE), which is conserved through many species and is required for maximal insulin gene expression [16].

Although EPAC1 activation is sufficient to induce SOCS3 expression in HUVECs, maximal SOCS3 gene expression also requires supporting activity from the MAP kinases, ERK and JNK [7,8].

To detect the highest proportion of true positives the analyses included only the following: (1) probe sets with Detection Above Background (DABG) p-value > 0.05 (2) exons with a gene level normalized log ratio between experimental conditions > 2, (3) t-test p-values < 0.05 (4) FDR p-value < 0.05 (5) maximal absolute gene expression change = 3 and (6) core level probe sets.

The additional use of the Tet-controlled silencer (tTS) caused almost complete abrogation of the leakiness of the Ptight promoter and an increase in the inducibility of the regulated gene, but the maximal levels of gene expression driven in the presence of Dox were also markedly reduced.

Maximal change in gene expression was typically observed already at the first time point examined (10 20 minutes after the onset of the perturbation).