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The improved activation during alkalosis, however, was not commensurate with changes in net muscle excitation or rapid and maximal force output which declined equally in both NaHCO3 and control conditions [117].
A baseline measure of maximal force output (pre-test) during a unilateral isometric squat was performed.
The standard error of the measurement was determined to be a 2.7%% change in maximal force output.
Table 6 shows the mean percent change of maximal force output according to diagnoses involving musculotendinous versus non-contractile structures.
Subjects that received the control and placebo treatment did not show an acute improvement in maximal force output.
Using a 95%% confidence interval, the minimal detectable change was determined to be 7.5%% change in maximal force output.
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Maximal force production was related to muscle weight.
To investigate whether deficits in force production in male KN1 mice could be accounted for by decreased TA mass, we calculated specific force (sPo), the maximal tetanic force output normalized for the cross sectional area of the TA muscle.
Thus, these variables were modeled by a linear regression [F V) = F 0 aV], where F 0 (force intercept at zero V), V 0 (velocity intercept at zero force), and maximum power output (P 0 = F 0 V 0/4) were considered as the maximal mechanical capabilities of the neuromuscular system to generate force, velocity, and power, respectively [65].
On the other hand, a recent study [ 54] found equal improvements in knee extensor maximal power output, rate of force development, and hypertrophy after 10 weeks of unilateral knee extension resistance training with low intensity (30% of 1 RM) lifted to failure versus high intensity (80% of 1 RM) lifted to failure.
Therefore, another approach consisted in the comparison of the load optimal for the maximal power output in a force-velocity test (Fopt = 0.5 F0) and the load optimal for peak power and mean power during all-out tests lasting 30 or 45 seconds [ 83, 104].
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