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Unique to tracheal strips from 1-wk-old animals, active force potentiated beyond the maximal force generated before oscillation.
The dependent variable was the maximal force generated during a unilateral isometric squat test.
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Muscle strength testing was conducted at each session using a dynamometer (Biodex-System 3, Biodex Medical Systems Inc., New York) to evaluate the relative changes in maximal force generating capacity over the time course of immobilization.
No effects on maximal force generating capacity of the myofilaments were observed, neither upon direct PKC treatment nor following phosphatase pretreatment.
Isometric force was measured in maximally activating calcium solution (pCa = −10log[Ca2+] = 4.5) and in relaxation solution (pCa 9.0) to determine maximal force generating capacity (Fmax) and passive force (Fpas), and normalized for cardiomyocyte cross-sectional area.
Studies in rodent myocardium indicated that cTnT and cTnI phosphorylation influence Ca2+ sensitivity and were involved in the PKC-mediated depression of the maximal force generating capacity [ 8, 18, 32, 33].
A significant rightward shift in optimal joint angle for force generation was also observed, indicating that maximal force was generated at a longer muscle length subsequent to damaging exercise.
The maximal force (Nm) generated during isometric knee extension and knee flexion.
Generally there is a length at which the force generated is maximal.
The force generated during maximal isometric force (MIF), and the height of jumping during vertical Squat Jumps (SJ) and Counter Movement Jumps (CMJ), were measured with a force plate (Kistler 2822A1-1, Winterthur, Switzerland) and sampled at 500 Hz.
Peak isometric force generated by the musculature was defined as the maximal load recorded during the test procedure.
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