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Ventilation tests, which measure the capacity of the lungs to move air in and out, include maximal voluntary ventilation (MVV), maximal air volume expelled in 12 15 seconds of forced breathing; forced expiratory volume (FEV), maximum air volume expelled in a time interval; and maximal expiratory flow rate (MEFR), maximal flow rate of a single expelled breath, expressed in litres of air per minute.
Paired measurements of maximal expiratory flow at functional residual capacity (V′maxFRC) were obtained ~3 weeks after birth in 24 preterm infants (gestational age [mean ± SD], 33.2 ± 2.2 weeks) and repeated at a corrected postnatal age (mean ± SD) of 57.0 ± 12.2 weeks.
Although the processes differ substantially they both lead to a common phenotype, reduced maximal expiratory flow.
Maximal expiratory flow was also was reduced in hyperoxic patients with no changes in normoxic ones.
Maximal expiratory flow volume curves (MEFV) curves are assessed in each child by means of the Flowscreen® (Jaeger, Wuerzburg, Germany).
Maximal expiratory flow lasts for only a fraction of a second and occurs very early in expiration.
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The mid-portion of the maximal expiratory flow-volume (MEFV) curve is often described by values of the mean forced expired flow as lung volume decreases from 75%to25%5% of vital capacity (ie, forced expiratory flow, midexpiratory phase [FEF25 75]).
This is shown in figure 7 and is analogous to the maximal expiratory flow-volume curve of the lung [32].
Forced expiratory volume in one second (FEV1), forced vital capacity (FVC) and FEV1/FVC ratio are measured; the spirogram (volume-time curve) and maximal expiratory flow-volume curve are also recorded.
However, the maximal expiratory flows did not differ between the two groups.
The differences of maximal expiratory flows measured by the thoracic and mouth pneumotachographs at this flow level were also elevated.
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