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Consistent with previously published cytological and transcriptional results, our single cell analyses revealed that while EC50 values were significantly different, at high concentrations of these steroids, maximal effects rivaled known agonists (Fig. 4, Supplementary Table S6).
Similar(59)
Spermine was the most effective polyamine, giving half-maximal effects at 170 microM and maximal effects at 400 microM.
Maximal effects of insulin alone were typically observed after ∼16 min of exposure, although in some cells, the increase was not maximal until 50 min or longer.
These laryngeal effects strongly depended on inlet Reynolds number, with maximal effects (approaching 15%) occurring at maximal inlet flow rates.
This is consistent with enhanced repressive effects of miRNA sites in close proximity and suggests that secreted parasite miRNAs could work in cooperation to exert maximal effects on host genes.
The maximal effects of PRL were noted at 24-48 h of incubation.
Both suppressed INS-1 cell death with similar maximal effects.
Minimalism produced for maximal effect.
Their painterly intensity and formal composition derive from Henri Cartier-Bresson's definition of photography as "the decisive moment," the juncture of maximal effect and maximal information.
In all cases, -JQ1 activity reached a plateau of maximal effect at 1 µM and was ineffective at 10 nM.
Our weak spots are endlessly exposed on TV and radio, showing terrorists where and how they can hit us with maximal effect without being intercepted.
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CEO of Professional Science Editing for Scientists @ prosciediting.com