Sentence examples for maximal effects on from inspiring English sources

This is consistent with enhanced repressive effects of miRNA sites in close proximity and suggests that secreted parasite miRNAs could work in cooperation to exert maximal effects on host genes.

This fluorescent analogue was designed to project the fluorophore into the adjacent protein cavity with minimal effects on receptor affinity and maximal effects on fluorescence polarization properties.

In contrast, ticlopidine marginally suppressed TRAP-mediated platelet activation at times when maximal effects on ADP-mediated platelet aggregation were evident.

Nevertheless, when multiple components are involved only some of which are known-it generally is unclear which should be targeted in order to have maximal effects on cellular performance.

However, unlike VCN which exerts its maximal effects on the actin cytoskeleton of HUVEC in the low nanomolar range (10 100 nM), the cyclic RGD peptide used in the study appears to have some minor effects on the actin cytoskeleton of these cells (i.e., partial disassembly of stress fibers) only at a much higher concentration (10 µM).

For behavioral experiments (2nd and 3rd experiments), a dose of 2 mg/ml of Dox was chosen because it was found to have maximal effects on neurogenesis in experiment 1. Animals were treated with Dox for seventeen weeks (experiment 2) or nineteen weeks (experiment 3).

The strength of the response is age dependent with the prepubertal period being the most effective stage for exercise to have maximal effect on bone mass [ 3– 7].

Maximal ΔMAP values of the 30 and 300 nmole groups in SHRs was not significantly different, suggesting that TCS-OX2-29 at 300 nmole might have nearly reached its maximal effect on the sucrose-agar consumption-induced pressor response.

Compound 12, N-{[ 6S,7R -7- 3,4-dichlorophenyl -1,4-oxazepan-6-yl]methyl}acetamide 0.5 fumarate, which showed effectively N-{[ 6S,7R -7- 3,4-dichlorophenyl -1,4-oxazepan-6-yl]methyl}acetamide-depeN-{[ 6S,7R -7- 3,4-dichlorophenyl -1,4-oxazepan-6-yl]methyl}acetamide

In short, the sexual strategising of males and females in some species reflects exactly those conditions that are good for Plasmodium survival.The findings are valuable clues in the battle against malaria; hijacking the hormone response, for example, could have maximal effect on only those species that pose the most danger.

When PLR induced the maximal effect on the stroke volume, hemodynamic measurements were recorded again.