maximal effect in

USAGE SUMMARY

The phrase "maximal effect in" is correct and usable in written English.
It can be used in contexts discussing the highest level of impact or influence within a specific area or situation. Example: "The researchers found that the drug produced a maximal effect in reducing symptoms after just one week of treatment."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

16 human-written examples

When given intravenously, the potent CGRP receptor antagonist olcegepant 2.5 most likely results in a maximal effect in the treatment of acute migraine [2].

The Journal of Headache and Pain

The unique requirements of the mandibular ridge geometry and the intraoral environment are that traditional bone tissue engineering technologies, created primarily to fill bone defects, be modified and optimized for maximal effect in the protruding alveolar ridge site.

Stem Cell Biology and Tissue Engineering in Dental Sciences

It has also found that the mechanical performance decreases with increase of the initial crack length for a given crack orientation, and that the initial crack orientation perpendicular to a tensile direction has a maximal effect in the reduction of the mechanical performance in this direction.

Composite Structures

This may be due to diltiazem having reached maximal effect in vivo at the lowest dose.

Plosone

However, these authors also pointed out that there was considerable pharmacokinetic and pharmacodynamic variance between individuals and that a dose of 4 mg/kg artesunate would be the minimum required to ensure a maximal effect in all individuals [7].

Plosone

In the INCAS trail, the maximal effect in the AZT+ddI+NVP group was observed at week 16, with 68% of patients demonstrating a pVL<20 copies/ml, with 51% maintaining this level of suppression at week 52.[7] One of the inclusion criteria of the INCAS trial was CD4+T cell count between 200 600/ul.

Plosone

Human-verified similar examples from authoritative sources

Similar Expressions

44 human-written examples

Source localization of alpha power, i.e. the difference in power between pause and observation intervals in the detection task, showed maximal effects in the left occipital gyrus, extending to the parieto-occipital sulcus dorsally (see Figure 3 left).

Plosone

This difference also led to maximal effects in the t-map at inferior and superior electrodes.

Behavioral and Brain Functions

From these data, concentrations of CNP that elicited maximal effects in vascular smooth muscle and endothelial cells (1 µM and 100 pM, respectively) were chosen for further experimentation.

British Journal of Pharmacology

Serotonin (30 μ m, a dose that produces maximal effects in cholinergic interneurons) induced reversible depolarizing effects (8.4 ± 3.6 mV) in 4/5 FSIs tested in the presence of TTX using conventional whole-cell recordings (Fig. 1C).

European Journal of Neuroscience

In addition, LL-37 has recently been shown to bind IAV, without aggregating or affecting haemagglutination activity, and to have maximal effects in vitro when pre-incubated with virus (although delayed addition of peptide or treatment of the cells, with washing before infection also has some antiviral effects) [ 135].

BioDrugs

Expert writing Tips

Best practice

When discussing interventions or treatments, use "maximal effect in" to highlight the point at which the greatest benefit is achieved. For example, "The drug reached its "maximal effect in" reducing inflammation after 72 hours."

Common error

Avoid using "maximal effect in" when you actually mean "optimal effect in". "Maximal" refers to the greatest possible effect, while "optimal" refers to the best or most favorable effect, which may not always be the highest. The drug might have a "maximal effect in" causing side effects, but its "optimal effect in" treatment may occur at a lower dosage.

Linguistic Context

The phrase "maximal effect in" functions as a noun phrase describing the point at which something achieves its greatest influence or impact. It is often used to quantify results or benefits within a specific domain, as demonstrated by Ludwig.

Expression frequency: Common

Frequent in

Science

98%

Formal & Business

1%

News & Media

1%

Less common in

Encyclopedias

0%

Wiki

0%

Reference

0%

Ludwig's WRAP-UP

In summary, the phrase "maximal effect in" is a grammatically sound and relatively common expression, particularly within scientific contexts, as validated by Ludwig. It describes the condition under which something achieves its greatest influence or impact. While alternatives like "optimal effect in" and "greatest effect in" exist, the specific choice depends on the desired nuance. When using this phrase, consider whether achieving the "maximal effect in" is truly the goal, or if an "optimal effect in" a trade-off is more desirable.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

Optimum effect in

Replaces "maximal" with "optimum", implying the best possible result within specific constraints.

Optimal effect in

Substitutes "maximal" with "optimal", suggesting the most favorable or desirable outcome.

Utmost effect in

Replaces "maximal" with "utmost", emphasizing the highest degree or level of influence.

Paramount effect in

Substitutes "maximal" with "paramount", indicating the supreme or most important impact.

High effect in

Replaces "maximal" with "high", denoting a significant but not necessarily the greatest impact.

Peak effect in

Suggests the greatest effect at a specific point or moment.

Possible effect in

Indicates the greatest effect that is achievable or feasible.

Full effect in

Suggests the complete or entire influence within a specific context.

Highest effect in

Highlights the supreme or most elevated impact within a context.

Greatest effect in

Substitutes "maximal" with "greatest", emphasizing the largest or most considerable impact.

FAQs

How can I use "maximal effect in" in a sentence?

You can use "maximal effect in" to describe when something reaches its highest level of impact or influence. For example: "The therapy showed its "maximal effect in" reducing pain after consistent application."

What are some alternatives to "maximal effect in"?

Alternatives include "optimum effect in", "optimal effect in", or "greatest effect in", depending on the specific nuance you want to convey.

Is it always desirable to achieve the "maximal effect in" a given situation?

Not necessarily. While a "maximal effect in" might be the goal in some cases, such as maximizing the efficiency of a process, it could be undesirable in others, such as when it leads to negative side effects. Often, the goal is to find the "optimal effect in".

What is the difference between "maximal effect in" and "maximum impact in"?

"Maximal effect in" and "maximum impact in" are very similar and often interchangeable. However, "effect" tends to refer to a specific, measurable result, while "impact" is broader and can include more general influences. The choice often depends on the specific context.