Sentence examples for maximal doses is from inspiring English sources

(C) Multiple drug therapy (two or more agents at maximal doses) is generally required to achieve blood pressure targets.

If needed to achieve blood pressure targets, a thiazide diuretic should be added to those with an estimated GFR (see below) ≥30 ml/min per 1.73 m and a loop diuretic for those with an estimated GFR <30 ml/min per 1.73 m. (C) Multiple drug therapy (two or more agents at maximal doses) is generally required to achieve blood pressure targets.

If needed to achieve blood pressure targets, a thiazide diuretic should be added to those with an estimated glomerular filtration rate (GFR) ≥30 ml/min/1.73 m and a loop diuretic for those with an estimated GFR <30 ml/min/1.73 m. (C) Multiple drug therapy (two or more agents at maximal doses) is generally required to achieve blood pressure targets.

If needed to achieve blood pressure targets, a thiazide diuretic should be added to those with an estimated GFR (eGFR) (see below) ≥30 ml/min/1.73 m and a loop diuretic for those with an eGFR <30 ml/min/1.73 m. (C) Multiple drug therapy (two or more agents at maximal doses) is generally required to achieve blood pressure targets.

If needed to achieve blood pressure targets, a thiazide diuretic should be added to those with an estimated glomerular filtration rate (GFR) (see below) ≥30 ml · min/1.73 m and a loop diuretic for those with an estimated GFR <30 ml · min/1.73 m. (C) Multiple drug therapy (two or more agents at maximal doses) is generally required to achieve blood pressure targets.

If needed to achieve blood pressure targets, a thiazide diuretic should be added to those with an estimated glomerular filtration rate (GFR) (see below) ≥30 ml/min per 1.73 m and a loop diuretic for those with an estimated GFR <30 ml/min per 1.73 m. (C) Multiple drug therapy (two or more agents at maximal doses) is generally required to achieve blood pressure targets.

Starting and maximal doses were relatively similar, suggesting limited titration after initiation.

For subjects weighing >40 kg, the maximal doses were: lisinopril 20 mg, losartan 50 mg, and atorvastatin 20 mg.

This underscores the challenges of the generalizability of this trial to older adults in clinical practice, where polypharmacy, pre-existing frailty, and conditions affecting tolerability of beta-blockers in maximal doses are more prevalent.

Therefore, in this study of the Arbeitsgemeinschaft Internistische Onkologie (AIO), we examined two sequential patient cohorts treated with different doses of docetaxel in combination with capecitabine to determine if maximal doses are really necessary in the palliative setting or if lower doses might have similar efficacy with better tolerability.

In the data presented in the Tables, the "Maximal" dose is always the 128µg/ml value.