Sentence examples for maximal dose and from inspiring English sources

Similarly, in type 2 diabetic patients with very poor metabolic control on maximal dose and number of agents, initiation of insulin may be the only solution to improve glycemic control and SMBG (47).

Psychiatrists are more likely to provide titration of stimulant doses with a lower initial dose, a higher maximal dose, and three or more visits in the first 90 days, suggesting increased monitoring [ 28].

This is because of the narrow therapeutic window, the systemic effects that appear above the maximal dose and the lack of further smooth muscle-relaxing effects above the maximal dose [ 12, 13].

In Egypt, the only available decoppering agent is D-PCA, so we tried hard to limit its side effects by starting therapy with a very small dose that was very gradually increased to reach the maximum desired dose meanwhile giving zinc sulphate starting with a maximal dose and gradually reducing it as D-PCA was increased.

The importance of testing high supra-therapeutic doses of the novel drug for the validity of the trial is emphasized, and the use of a dose run-up pilot study for selecting maximal doses and matching doses between the novel and comparison compound is explained.

All drugs were administered at maximal doses, and they did not have unacceptable side effects.

Besides DDIs, users are informed about double medication, incompatibility, exceeded maximal doses and the risk of kidney insufficiency due to the patient's pharmacotherapy.

In devising research involving antidepressants for PLWHA, however, clinicians should control for the stage of HIV illness, co-morbid illnesses such as hepatitis B and C, the potential for drug interactions with cART, type of ADT, maximal dosing and participants' preferences [ 133, 141– 141].

Plans were processed using intensity modulated therapy by means of volumetric modulated arc therapy in its RapidArc form (Varian medical system, Palo Alto - USA) to ensure maximal dose conformity and rapid dose falloff toward critical structures.

The glycemic benefits of sulfonylureas are nearly fully realized at half-maximal doses, and higher doses should generally be avoided.

A 20-mg limit for glipizide was chosen because the glycemic benefits of sulfonylureas are virtually complete at half-maximal doses, and higher doses are generally not recommended (2).