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Each joint was scored from 0 (normal) to 5 (maximal destruction).
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Maximal tissue destruction would perhaps have overridden its protective effect since no additional immunosuppressive therapy was employed.
The final arthritis score was evaluated for each animal by calculating the sum of the values for inflammation and destruction (maximal evaluation grade = 12) as described elsewhere [ 20].
It is also required to achieve maximal suppression of bone destruction during the treatment of RA patients with TNF-alpha-inhibitor [ 16].
Post-mortem analyses of nigrostriatal integrity demonstrated that nigrostriatal destruction was already maximal by wk 1 in lesioned animals with no further increase at 3 or 5 wks.
Acetone exhibits the least exergy destruction, while R245fa possesses the maximal exergy efficiency at a fixed PPTD.
I'm austerely maximal.
But the parts are maximal.
Unbelievable destruction.
"Complete destruction".
Defense rewards maximal effort.
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