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Firstly, a supra-maximal current intensity was established at which the amplitude of the compound C-fibre response was maximal and this was designated a 100% response (100%, Figure 1A).
To further determine latency and current threshold for the first measurable CMAP as well as CMAP amplitude, latency, and current intensity for the evocable maximal CMAP (M CMAP amplitude), the nerves were stimulated with continuously increasing current intensity from 0.1 mA until the CMAP shape and amplitude did not change any longer [ 32].
As a result, in alert patients, current intensity was initially set to the maximal tolerated level, and was increased by 10% (or less, if the patient felt discomfort) every three minutes.
A further increase in humidity to 87% not only increases maximal current in components 1 and 2, but also leads to intensity shift from component 1 to component 2 in the abundance maps (cf. Figure 9e,i and Figure 9f,j pairwise), i.e., decreasing the height of potential barrier of electron/hole injection from the tip into the nanocomposite.
Activation of the preparation was accomplished by electrical field stimulation using a current stimulator (701C, Aurora Scientific), and the current intensity of 0.2 ms duration stimulus pulses was adjusted to elicit maximal active force.
For neurogenic dural vasodilation, we initially started with a current intensity (monitored on an oscilloscope, model 54601A, Hewlett Packard, Palo Alto, CA, U.S.A). of 100 μA and increased with 50 μA steps until a maximal level of dilatation was achieved, usually at 200 μA.
The current intensity was 26 μA.
Penicillin (5 mM), in contrast, significantly reduced maximal current amplitudes and decreased the concentration required to trigger currents with half maximal amplitudes (Table 1 and Figure 6B).
(D ) Spike parameters of the example cells at lower current intensities (d V/ d t: maximal rate of rise, thr: action potential threshold).
In addition, strength contraction and current intensities were not systematically recorded, which could possibly allow for further insight into the potential mechanisms of EPCs mobilization; however, by design, current intensities applied optimally aiming at full muscle contraction were the maximal tolerated by non-sedated and sedated patients, implying maximum applicable contraction in each case.
The current efficiency defined as the maximal EL intensity divided by the current density is 597.8 mA cm-2 for multi, and 483.9 mA cm-2 for single.
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