In all three repetitions, at least two peptides corresponding to AMOT p130 were identified in the tryptic digest, and the maximal coverage was 33% (see Figure 1 figure supplement 1).
Since a too large coverage yields very small precision, and a too small coverage yields very small recall, all quality functions obtain maximal F-measure when the coverage is ~2000 to 3500.
In Figure 6(b), we can clearly see that the upper bound of coverage improvement is small when the expected coverage is near 0 or 1, and is maximal when the expected coverage is near 0.6.
As expected, the benefit of the vaccine programme increases as vaccine effectiveness and coverage increase, indicating that achieving and maintaining high coverage is important in all subgroups to get a maximal benefit from the vaccine program.
When identifying features, coverage is taken additively across samples from the same genome and merged to yield a maximal set of features (Stage 2).
Insurance coverage is scant.
Now, coverage is everywhere.
But coverage is sporadic.
