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The maximal concentration was found at 12 00 AM in the third pig.
After equilibration, the near maximal concentration was induced by PE (0.3 μM).
Selenium was not shown to stimulate photosynthesis of Euglena gracilis [29]; however, in that study, selenite was used and its maximal concentration was tenfold lower than in our research.
Based on the ELISA method, we determined the level of serum dTMP-GH fusion protein in rabbits, which revealed the maximal concentration was 13.60 ± 4.08 ng/mL 30 min after injection and showed gradual decrease later until reaching the baseline level 2 h after administration (Fig. 5b).
Time to maximal concentration was 11.9 minutes [5.00 60.0] for dihydroartemisinin.
Only in the liver the mesna concentrations decreased immediately after the maximal concentration was observed at 5 min after administration.
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Three phase I studies to evaluate its pharmacokinetic profile have shown that granisetron administered by a transdermal delivery system is absorbed by passive diffusion and maximal concentration is reached 48 hours after patch application.
Recovery from both compounds, even at maximal concentrations, was rapid, and no mortality out to 24 h was noted.
None of the remaining compounds/oils used at the maximal concentrations was able to improve significantly the inhibitory effect produced by 30 μM α-T on lipid peroxidation, in both the cell lines and all experimental conditions.
We found that half-maximal time T50 (i.e., the time required for culture to reach half-maximal concentration) was inversely proportional to the initial culture concentration (see Figure S4 in File S1).
Maximal concentrations were reached at 3 h post i.p. administration and declined thereafter with no detectable plasma concentrations at 24 h (Fig. 3a).
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