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Notably, the PRR9 expression level was not maximal compared to peak levels, suggesting that another factor is involved in the gating of light responses in the dark.
However, quantitative analysis of autophagy and mitophagy suggests that AV up-regulation by Bnip3 is not maximal compared to the activation of autophagy by mTOR inhibition (Figs. 4a and 5a), and we show that by inducing autophagy with CCCP in HeLa cells, sequestration for both WT and 2SE Bnip3-targeted mitochondria was significantly increased (Fig. 5b).
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The absence of RNase L siRNA effect on insulin response in Myo-siRNaseL could be explained by the fact that, at these concentrations of palmitate, inhibition of insulin response is yet maximal (compare insulin-stimulated P-Akt/Akt expression rate in cells transfected with Control and RNase L siRNA in Figure 2c).
The goal is to find a subset of the set with one potential promoter in each region such that their total pair-wise similarity is maximal comparing to any other collection of potential promoters in that subset; the subset size is simultaneously maximized.
By using sub-maximal testing we also decrease the number of excluded participants since a larger number will have the needed qualifications to carry out a sub-maximal test compared to a maximal test.
Fig. 5 Theoretical predicted maximal values compared with FDTD simulations.
CART was also associated with significant increase in peak oxygen uptake and maximal workload compared to the SG (p < 0.05).
Motor test data are presented as percentages of the maximal duration compared with the internal baseline control (before ICH).
In the agonist activity assay, calycosin showed ERα selectivity with a 2-fold reduction in EC50 value and a 2-fold increase in maximal activation compared with ERβ (Fig. 5B i).
The helical blades (PFN A/TFN) show for both directions higher maximal torques compared to the screws (DHS/Gamma3).
Potencies were defined as percentage maximal increase/decrease compared with untreated controls.
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