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From this plethora of pharmacological possibilities, can we design ligand properties that would deliver maximal clinical efficacy with lowest toxicity?
Pad placement will be directed by the provider to provide maximal clinical efficacy.
To achieve maximal clinical efficacy we found the most common number of titrations was 2 with an increasing proportion of patients on 37.5 and 50 mg dosages during the time-course of the study.
By combining these approaches, the next generation of GPCR ligands will unquestionably be more sophisticated, employing rational design principles to deliver GPCR ligands with low toxicity with maximal clinical efficacy.
Selective inactivation of multiple kinases is not an undesirable pharmaceutical profile for a small molecule inhibitor and, in fact, could be the best strategy to achieve maximal clinical efficacy of an anti-cancer agent [ 38].
Similar(55)
Clinical efficacy of antimicrobial mouthrinses.
They have 25 years building spirometry with a real level of clinical efficacy.
However, their clinical efficacy and safety lack systematic evaluation.
Further studies will be needed to verify the clinical efficacy.
We showed biological efficacy in all 5 indications, although clinical efficacy was uneven.
The results confirm clinical efficacy of PMR for migraine prophylaxis.
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