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UB Maximal cell size.
The main constraints are maximal cell size and machine time-capacity.
Partly, this result depends on our definition of a constant maximal cell size in the model (Methods).
Some answers to the question how ethylene/ACC controls the maximal cell size in roots are found in the published literature and will be briefly discussed here.
This estimation was performed on a regular grid composed of 2 equally spaced points on [ 0, A m a x ] and 2 equally spaced points on [ 0, X m a x ], where A m a x is the maximal cell age in the data and X m a x the maximal cell size (for instance A m a x =60 min and X m a x =10 µm for the experiment f1, as shown in Figure 3A).
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To achieve the >70% increase in maximal cell density without additional supply of nutrients the cells underwent an overall reduction of 14% in size as well as a significant decrease in glucose and amino acid consumption rate.
The current voltage (I-V) relationship of total Na+ current normalized to the cell size shows that these neurons produced a large amplitude Na+ current upon membrane depolarization, reaching maximal amplitude at -20 mV.
Upper cell size limit.
Lower cell size limit.
The absence of an additive increase in cell size with the combination of PE stress and myostatin inhibition may indicate that our potent, protease-resistant myostatin inhibitor and PE stress independently achieved maximal pathway activation at the doses administered.
Cell size was quantified using SigmaScan Pro.
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