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The specific physical capacity measurements are chosen based on three main criteria: 1) reasonably high validity with more rigorous capacity measurements [ 44- 46] 2) relation with physical work capacity [ 36, 47] and 3) suitability as field measures – low performance requirements for the participants (compared to i.e. maximal capacity tests), low costs and easy to move around.
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The maximal exercise capacity test was repeated for all animals after five weeks (test 2).
Due to the practical considerations of performing a maximal aerobic capacity test, a peak oxygen consumption (VO2peak) test was chosen.
Subjectively, participants were well acclimatized to high altitude with no evidence of acute high altitude illness at the time of the study and had no contraindications to undertake a maximal exercise capacity test.
Afterwards, a maximal exercise capacity test (test 1) was performed with a 5-minute warm-up (25% inclination, 0.2 km/hour) followed by an increase in treadmill speed (0.1 km/hour every 2.5 minutes) until animal exhaustion, that is, until they were not able to run even after 10 mechanical stimuli.
Beside laboratory parameters, different quantitative liver function tests such as ICG clearance or maximal liver function capacity test (LiMAx) or tests for evaluation of hepatic blood flow (galactose clearance) aim to facilitate assessment of liver function in acute and chronic hepatic impairment [4, 32, 33].
The new maximal liver function capacity test (LiMAx test) is a real-time method to investigate the liver function.
Beside laboratory parameters, different quantitative liver function tests such as ICG clearance or maximal liver function capacity test (LiMAx) or tests for evaluation of hepatic blood flow (galactose clearance) aim to facilitate assessment of liver function in acute and chronic hepatic impairment [ 4, 32, 33].
In patients with COPD, serum lactate was found to increase up to the maximal capacity during a stepwise exercise test on an ergocycle [ 26].
The following criteria were used to determine maximal capacity for oxygen consumption at the test: the subject reached volitional fatigue, respiratory exchange ratio (RER) ≥1.15, HRtest ≥95% of age-predicted maximum HR (220 – age), and/or a plateau in oxygen consumption with increasing load.
Furthermore, exercise capacity tests are, by their very nature, maximal and will, therefore maximally stress the homeostasis of the internal environment.
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CEO of Professional Science Editing for Scientists @ prosciediting.com