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Moreover, it could be shown that fractionating the light dose enhances the effect of PDT only in surrounding but not in tumour tissue, since oxygen supply in tumour tissue is already maximal because of the characteristic structural and functional abnormalities of the tumour microvasculature.
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However, such weighting function does not give maximal SNR because of bias effects: for example, an initially very large intensity y ij may become less than 2 B − 1 with a certain probability, due to addition of offset noise or FPN, but without being affected by the clipping operation.
Running Flip several times may generate different maximal bipartitions, because of the random choices in initializing vertices to partitions, and also because of the random choices of which unhappy node to switch to happy at each iteration of the while loop.
As in the other mechanism leading to path-dependency (the actor similarity mechanism), the number of components becomes maximal because every actor chooses not to deviate from their previous concept anymore.
Delineating the boundaries of cerebral gliomas plays a vital role in glioma surgery because maximal resection of gliomas contributes greatly to prolonged survival, reduced rates of recurrence and morbidity [ 5, 29].
Second, because maximal activation of β-catenin has previously been suggested to be incompatible with MET (Kuure et al., 2007; Park et al., 2007, 2012), we identified CHIR concentrations that induced nephron differentiation (PAX2 and PAX8 expression) but still permitted epithelialisation (CDH1 expression; Figure 2 figure supplement 2).
This 2-h interval was chosen because maximal synergism of NGR hTNF with cytotoxic agents was observed with a 2-h delay between NGR hTNF and chemotherapy administration (Sacchi et al, 2006), thus suggesting a maximum drug effect on the vasculature at that time point.
For example, PX174 achieves only 50% of its potential maximal fitness (r) because of sub-optimal thermoregulatory behavior.
The heart in this experiment was already in maximal hyperaemic state, because of its removal from the pig body [ 9].
For the former, however, three participants were instructed not to perform maximal level exercises because of their hypertension.
We focused on the maximal network component because of space limitation and on chemical substructures and protein domains whose weights were higher than 0.4 in the case of the L1SVM method for visualization simplicity in the figure.
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