Sentence examples for maximal bactericidal activity from inspiring English sources

In conclusion, we have successfully identified shorter, inexpensive fragments with maximal bactericidal activity.

A 10% povidone-iodine solution was diluted to achieve a concentration of 3.5% betadine, possessing maximal bactericidal activity and minimal cytotoxicity.

However, this is mitigated by evidence suggesting that dosing with either delamanid 100 mg twice daily or 200 mg twice daily results in concentrations above the exposure threshold for maximal bactericidal activity (unpublished data).

Carbapenems require a T > MIC of at least 40% of their dosing interval for maximal bactericidal activity, and attainment of this pharmacodynamic target depends on dosage, individual patient pharmacokinetics, and the MIC of the target pathogen.

Classical studies report that penicillins and monobactams require at least a 50 to 60 % T>MIC for maximal bactericidal activity, cephalosporins require a 60 to 70 % T>MIC and carbapenems require a 40%% T>MIC[ 54].

For time-dependent antimicrobials, the PD parameter most predictive of maximal bactericidal activity is the duration of time in which free drug concentrations remain above the MIC during the dosing interval (ƒT >MIC).

Maximum bactericidal activity was observed against Pseudomonas aeruginosa 3.

In the current investigation, agr dysfunction resulted in attenuation of vancomycin killing activity with decreases in maximal effect and lack of bactericidal activity against both HA-MRSA and CA-MRSA.

The bactericidal activity of doxycycline is maximal at pH 6.6.

GM-CSF activates monocytes and enhances their bactericidal activity [11] [13].

At the therapeutic range of both useful and safe ozone concentration for performing O3-AHT, the maximal H2O2 concentration can be about 40  μM, but it cannot display bactericidal activity because it has a half time less than 1 min and a very fast dilution into the intracellular water of blood cells.