On the other hand, larger average mutual distances between all pairs of signals (E1, E2, NX, FWC) and larger average maximal area were observed for the larger chromosome (XL) in comparison with the smaller one (XS).
While incidence rates were low, BMLs (assessed by measuring maximal area) were not static, with around half either worsening or improving over the study time-frame.
In a population based sample, BMLs (assessed by measuring maximal area) were not static, with similar proportions both worsening and improving.
In conclusion, BMLs (assessed by measuring maximal area) were not static, with similar proportions both worsening and improving in this population-based sample.
The maximum area number at each node was set as two in the final analyses but alternative analyses with three or more maximal areas were carried out for comparison.
While the IOS spreads smoothly and homogeneously, however, the VSD signal shows marked variability in the spatial spread of each wave (Fig. 8 B ). Averaging over 8 animals in which simultaneous data were acquired during the evolution section, the maximal VSD area was 10.07 ± 1.91 mm, which is smaller but not statistically different than the maximal area of CBV spread (11.23 ± 2.62 mm).
The color Doppler maximal jet area was used to assess the severity of TR.
For the evaluation of the tumour size, the maximal tumour area was measured in H&E-stained brain sections of each animal.
For quantitative determination of the tumour size in each animal the maximal tumour area was determined in serial H&E stained tissue slides using an Axioskop microscope (Carl Zeiss Microimaging, Göttingen, Germany) and a Neurolucida software-controlled computer system.
Maximal swelling area was then estimated for each cycle of each female by averaging across contours.
