Sentence examples for maximal activation after from inspiring English sources

Poly-l-arginine activated p38 MAPK phosphorylation, with a maximal activation after 30 min. In 16HBE14o- cells, IL-8 release may also be regulated by the ERK1/2 pathway [47], [48].

We determined that caspase 8 activity increases in a time-dependent manner with a 2-fold maximal activation after roughly two hours of culture in DM (Fig. 1(A)).

ERK phosphorylation in IGFIR-10A cells is transient in response to insulin or IGF-I stimulation in monolayer culture, with maximal activation after five minutes.

Leptin enhanced p38MAPK phosphorylation (Figure 1B) in a time-dependent manner (data not shown) with maximal activation evident after 10 minutes.

The maximal activation was achieved after 10 min, followed by a rapid decline in phosphorylated ERK1/2.

JNK was strongly activated by HGF, reaching maximal activation as early as 5 10 minutes after HGF addition (Fig. 3C).

Western blotting confirmed that maximal activation occurs 3 6 hours after Dox treatment (Figure 1C), and is maintained at peak levels over a long period (24 hours Figure S1).

In initial time course experiments, we found significant phospho-Akt upregulation as early as 2 minutes with maximal activation at 10 15 minutes after exposure of EGNP-1-transduced HUVEC to EGF (Figure 3e).

Oxidative stress, which occurs mainly after maximal activation of neutrophils and establishment of shock [ 9], has been shown to induce a proinflammatory cytokine response [ 10, 11].

Western blotting analysis showed that the amount of phosphorylated PAK1 at Thr 423 was increased significantly from 5 to 30 min after LPA stimulation with maximal activation at 15 min. However, after 30 min it declined toward basal levels (Fig. 3A and B).

VEGF164 treatment increased the phosphorylation of AKT1 and ERK1/2, with maximal activation for each pathway 5 minutes after VEGF addition and with comparable activation kinetics, either after serum starvation overnight (Fig. 6A,B) or for 72 hours (Fig. 6C,D).