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They suggest that it might be useful to establish a deposition system to which authors can submit their data to ensure maximal accuracy and accessibility and to replace possibly the traditional retrospective process of manual data extraction.
Magnetic resonance imaging (MRI), like CT, can separate visceral fat from subcutaneous fat and since there is no radiation involved, it can perform a total body scan for maximal accuracy and fat distribution.
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On classification of group II alternatively spliced exons against a constitutive background, we achieved a maximal accuracy of ∼66% and AUC of 0.71 in IMR90.
At best, we achieved a maximal accuracy of 80% and AUC of 0.88 for classifying distal group II alternative exon intron boundaries against the constitutive background in IMR90.
In H, we observed the same trend (data not shown) and obtained a maximal accuracy of 76.5% and AUC of 0.84 for classification of group I exon intron junctions against distal constitutive ones.
The CC and HC-based models as standalones performed even worse with the maximal accuracy of 73.55% and 73.31% respectively.
In H, we achieved a similarly high level of accuracy of performance with a maximal accuracy of 78% and AUC of 0.87.
We obtained the best possible accuracy of classification with an AUC of 0.84 and maximal accuracy of 77.1% by using a filtering distance of 10 kb for determining the set of distal constitutive exon intron boundaries in IMR90.
It turns out that the stationary point equations are fulfilled with an average accuracy over all states and stationary points of 0.002 and a maximal accuracy of 0.006, which both is (<10^{-2}).
Based on the predicted optimal parameters, we obtained an AUC of 0.875) and an maximal accuracy of 0.803), which are both higher than the MEME-based prediction, of which the AUC is 0.86 and maximal accuracy is 0.78 [ 5].
However, we obtained anAUC of0.853 and a maximal accuracy of 0.789, suggesting a slightly reduced prediction power when discarding RNA secondary structure information (Additional file 2).
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CEO of Professional Science Editing for Scientists @ prosciediting.com