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Cartilage-specific β-catenin signaling regulates chondrocyte maturation, generation of ossification centers, and perichondrial bone formation during skeletal development.
In mammals studied prior to skeletal maturity, administration of estrogens produces an accelerated appearance of ossification centres, a slowing in growth of cartilage and bone, and fusion of the epiphyses; the result is an adult skeleton smaller than normal.
Both plain radiographs and CT imaging are the standard references to assess HO maturity, since CT more accurately defines the different stages of ossification than do plain radiographs.
Plain radiographs and CT may show various phases of ossification: amorphous calcification, immature and mature ossification.
Zone of ossification: Osteoblasts deposit bone matrix on the exposed plates of calcified cartilage.
The mode of ossification of the long bones is characteristic.
He is 70, into the years of ossification, and his political triumph has only convinced him of his inerrant correctness.
That happens to correspond to an area of ossification, fusing pairs of vertebra and otherwise indicating injuries from repeated stress.
Centres of ossification sometimes develop in nonbony connective tissue.
This ossification front is formed by chondrocytes from the germinal zone through a process of mineralisation and ossification, and (c) the process of mineralisation and ossification has a certain morphological analogy to the process of ossification in the metaphyseal cartilage of amphibians and differs from the endochondral ossification process in the metaphyseal side of the growth plate.
In the cervical spine, the combination of ossification of the ligamentum flavum (OLF) and ossification of the posterior longitudinal ligament (OPLL) is rarely seen.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com