The circadian timing system develops prenatally and matures progressively after birth [ 34].
The internodes mature progressively towards the base of the culms with an increasing concentration of sucrose at the base.
Furthermore, during MTB infection, activated macrophages ingesting micro-organisms generate phagosomes that mature progressively along with the endocytic pathway, leading to fusion with late endosomes and ultimately to the formation of lysosomes [ 43, 44].
This has been discovered in the Medicago truncatula- Sinorhizobium meliloti symbiosis, which leads to the development of root nodules where bacteria inside the plant cells mature progressively to nitrogen-fixing bacteroides.
As cells mature, they progressively lose expression of progenitor markers and acquire markers of mature oligodendrocytes, including MBP, MAG and CNP[29], [30].
Through a network of progressively maturing vesicles, the endosomal system connects the cell's interior with extracellular space.
Normally germ cells mature in a gradient, with GSCs at the distal end, differentiated gametes at the proximal end and progressively maturing germ cells in between.
Whether this progressively maturing retirement savings scheme could obviate at least some of the old age allowances currently in place remains to be examined although there would be tremendous political pressure against government withdrawing from such age-based welfare support.
In both the human [ 16] and the rhesus macaque [ 15], NLRP11 and 13 have been found specifically or preferentially expressed in the oocyte, with a similar expression pattern to other oocyte-specific NLRP genes, i.e., enriched in maturing oocytes and then progressively diminished in embryos, indicating an exclusive maternal origin of these transcripts.
Both of these cell types can give rise to all lineages of intestinal cells, including the transient amplifying (TA) cells that lie immediately above ISCs and move progressively upwards while maturing to eventually reach complete maturation close to the opening of the crypts.
As cells within the tumor mature, they become progressively more restricted in the cell types to which they can give rise.
