Sentence examples for maturing dendritic cells from inspiring English sources

The up-regulation of genes associated with dendritic cell maturation could indicate the presence of maturing dendritic cells in peritoneal fluid, or perhaps more likely, the activation of macrophages (the predominant cell type in the peritoneal cavity at 2 h), which express many of the same markers as dendritic cells.

Our work suggests that, as in maturing dendritic cells, increased assembly of the V-ATPase sectors along the endocytic pathway of fibroblast-like cells contributes to increasing the acidity of the organelles.

The higher V1/V0 ratio in late vs. early endosomes correlates with the higher acidity of this compartment, suggesting that an increase in V-ATPase activity through an increase in V1-V0 associsthen is the underlying mechanism and that this mechanism of regulation is not restricted to yeast [14], [60] and maturing dendritic cells [16].

Its corresponding receptor CCR7 is expressed on naive T cell subpopulations and up-regulated by maturing dendritic cells [ 34].

Other sources of IL-20 are keratinocytes (KCs) [ 14, 15], maturing dendritic cells (DCs) [ 16], synovial fibroblasts [ 17], endothelial cells [ 18, 19], and renal mesangial cells [ 20].

Indeed, interactions between T cells and antigen-presenting dendritic cells, critical to the development of an adaptive immune response, have recently been observed in IPF lung, in the form of tertiary lymphoid follicles, composed of reactivated T cells, B cells and locally maturing dendritic cells (Marchal-Somme et al., 2007).

CD137 ligand agonists also induce differentiation of peripheral human monocytes to mature dendritic cells (DCs) [17], [18] as well as DC maturation [19] [21].

The contribution of iNKT cells in immune surveillance is at least partly based on their capacity to mature dendritic cells (DC) and subsequently activate natural killer (NK) cells, the latter of which become potent cytotoxic cells.

It also regulates antigen presentation by dendritic cells and shifts mature dendritic cells to immature precursor cells.

Both proteins signal via TLR2 and are able to mature dendritic cells [ 62].

Exogenous antigen activates and matures dendritic cells leading to costimulatory molecule expression and Th1, Th2, or Th17 cell activation [ 102].